Cheesy Chicken Tetrazzini

Cheesy Chicken Tetrazzini – comfort food at its best! Chicken and spaghetti baked in a homemade cheese sauce. So easy to make and the whole family loved it! Chicken, spaghetti, butter, flour, milk, cheddar cheese, cream of chicken soup, garlic powder, Worcestershire sauce, salt, and pepper. Can add bell pepper, pimentos, green peas, or spinach to the casserole. Can make in advance and freeze for later. #casserole #chicken #spaghetti #cheddarcheese

chicken tetrazzini in baking dish

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Easy Chicken Tetrazzini Recipe

Chicken Tetrazzini is a very popular chicken casserole. It seems like most families have their own version of this classic dish. This Cheesy Chicken Tetrazzini recipe comes from a Plain Chicken reader. I love Chicken Tetrazzini, so I am always up to try a new version, and this version is delicious! Chicken, spaghetti baked in a creamy cheese sauce. I could have eaten the whole pan myself!

chicken tetrazzini in a baking dish

How to Make Chicken Tetrazzini Casserole

This Cheesy Chicken Tetrazzini Casserole is very easy to make. Start by cooking the spaghetti. While the spaghetti is cooking, start on the sauce. Melt some butter in a saucepan. Whisk in some flour and cook for a minute. Slowly whisk in some milk. Do this slowly so the sauce doesn’t get lumpy. Let the sauce cook a couple of minutes until it starts to thicken. Remove the sauce from the heat and whisk in some cheese, a can of cream of chicken or mushroom soup, garlic powder, Worcestershire, salt, and pepper. Finally, toss together the cooked spaghetti, cooked chicken, and the sauce. Spread into a baking dish and top with more cheese. Pop the casserole in the oven and bake.
The original recipe included a bell pepper and a 4-oz jar of diced pimentos. I don’t particularly love either, so I left them out. Feel free to add them to the casserole if you enjoy them. You could also add some frozen green peas or spinach. Both sound delicious!

Can Chicken Spaghetti Be Frozen?

You can make this Cheesy Chicken Tetrazzini ahead of time and refrigerate or freeze for a quick meal later. To bake the casserole after freezing, thaw completely in the refrigerator overnight and bake as directed below. To reheat the casserole, thaw completely in the refrigerator overnight. Cover with foil and bake at 350ºF for 30 to 40 minutes, until heated through.

plate of chicken tetrazzini casserole

What to Serve with Chicken Tetrazzini

This Cheesy Chicken Tetrazzini is a new favorite at our house. We both loved this easy cheesy chicken spaghetti. I actually have it on the menu again this week. YUM! We love to serve this with a salad, green beans, asparagus, and some bread. Here are a few of our favorite recipes from the blog that go great with this yummy Cheesy Chicken Tetrazzini Casserole:

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plate of pimento chicken spaghetti casserole with text overlay

Pimento Cheese Chicken Spaghetti

Yield: 6 people
Prep Time 15 minutes
Cook Time 30 minutes
Total Time 45 minutes
Pimento Cheese Chicken Spaghetti – comfort food at its best! Chicken, diced pimentos, and spaghetti baked in a homemade cheese sauce. Kids and adults gobbled this up! Chicken, spaghetti, butter, flour, milk, cheddar cheese, cream of chicken soup, garlic powder, onion powder, diced pimentos, Worcestershire sauce, salt, and pepper. Perfect for busy weeknights or special occasions, this recipe is sure to become a family favorite.

Ingredients:

Instructions:

  • Preheat oven to 350ºF. Lightly spray a 9×13-inch baking dish with cooking spray.
  • Cook spaghetti according to package directions. Drain.
  • In a saucepan, melt butter over medium heat. Whisk in flour and cook 1 minute. Slowly whisk in milk and cook until it starts to thicken, 3 or 4 minutes. Remove from heat.
  • Stir in 1 cup cheddar cheese, cream of chicken or mushroom soup, garlic powder, onion powder, salt, pepper, and Worcestershire sauce.
  • Add chicken, pimentos, and cooked spaghetti to cheese sauce and mix well.
  • Transfer spaghetti mixture to prepared baking dish. Sprinkle with remaining ½ cup cheddar cheese.
  • Bake for 30 to 40 minutes.

Notes:

  • I use rotisserie chicken in this recipe, but you can use any cooked chicken you have on hand. Chicken breasts, chicken thighs, tenderloins, or canned chicken all work great.
    • You can substitute leftover holiday turkey.
  • I suggest using Unsalted Cream of Chicken & Mushroom Soups in this dish to control the sodium.
  • Cook the spaghetti noodles in chicken broth for extra flavor.
  • Variations/Additions:
    • onions
    • bell peppers
    • spinach
    • green peas
  • Can Chicken Spaghetti Be Frozen? Yes! Assemble the casserole and cool to room temperature. Cover the pan with plastic wrap and aluminum foil. Store in the freezer for up to 3 months. 
    • When ready to bake, thaw overnight in the fridge and bake as directed.
  • Can I make Chicken Spaghetti In advance? Yes! You can definitely make the casserole ahead of time. Assemble the casserole and cover the pan with plastic wrap or aluminum foil. Store in the refrigerator for up to 3 days
    • Bring the casserole dish to room temperature before baking as directed. 
  • Store leftovers in an airtight container in the refrigerator.
    • Reheat in the microwave.

Steph

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